EC 6.3.2.33 - Tetrahydrosarcinapterin synthase

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IntEnz Enzyme Nomenclature
EC 6.3.2.33

Names

Accepted name:
tetrahydrosarcinapterin synthase
Other names:
H4MPT:α-L-glutamate ligase
MJ0620
MptN protein
Systematic name:
tetrahydromethanopterin:α-L-glutamate ligase (ADP-forming)

Reaction

Comments:

This enzyme catalyses the biosynthesis of 5,6,7,8-tetrahydrosarcinapterin, a modified form of tetrahydromethanopterin found in the Methanosarcinales. It does not require K+, and does not discriminate between ATP and GTP [1].

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Protein domains and families: PROSITE:PDOC50975
Structural data: CSA , EC2PDB
UniProtKB/Swiss-Prot:

References

  1. Li, H., Xu, H., Graham, D. E., White, R. H.
    Glutathione synthetase homologs encode α-L-glutamate ligases for methanogenic coenzyme F420 and tetrahydrosarcinapterin biosyntheses.
    Proc. Natl. Acad. Sci. USA 100: 9785-9790 (2003). [PMID: 12909715]

[EC 6.3.2.33 created 2010]