EC 3.2.2.25 - N-methyl nucleosidase

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IntEnz Enzyme Nomenclature
EC 3.2.2.25

Names

Accepted name:
N-methyl nucleosidase
Other names:
7-methylxanthosine nucleosidase
N-MeNase
N-methyl nucleoside hydrolase
methylpurine nucleosidase
Systematic name:
7-methylxanthosine ribohydrolase

Reaction

Comments:

The enzyme preferentially hydrolyses 3- and 7-methylpurine nucleosides, such as 3-methylxanthosine, 3-methyladenosine and 7-methylguanosine. Hydrolysis of 7-methylxanthosine to form 7-methylxanthine is the second step in the caffeine-biosynthesis pathway.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , DIAGRAM , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
Gene Ontology: GO:0033960

References

  1. Negishi, O., Ozawa, T. and Imagawa, H.
    N-Methyl nucleosidase from tea leaves.
    Agric. Biol. Chem. 52: 169-175 (1988).

[EC 3.2.2.25 created 2007]