EC - Methylthioribulose 1-phosphate dehydratase

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IntEnz Enzyme Nomenclature


Accepted name:
methylthioribulose 1-phosphate dehydratase
Other names:
1-PMT-ribulose dehydratase
S-methyl-5-thio-D-ribulose-1-phosphate hydro-lyase
Systematic name:
S-methyl-5-thio-D-ribulose-1-phosphate 4-hydro-lyase [5-(methylsulfanyl)-2,3-dioxopentyl-phosphate-forming]



This enzyme forms part of the methionine-salvage pathway.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , DIAGRAM , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
Gene Ontology: GO:0046570
UniProtKB/Swiss-Prot: (196) [show] [UniProt]


  1. Furfine, E.S. and Abeles, R.H.
    Intermediates in the conversion of 5'-S-methylthioadenosine to methionine in Klebsiella pneumoniae.
    J. Biol. Chem. 263: 9598-9606 (1988). [PMID: 2838472]
  2. Wray, J.W. and Abeles, R.H.
    The methionine salvage pathway in Klebsiella pneumoniae and rat liver. Identification and characterization of two novel dioxygenases.
    J. Biol. Chem. 270: 3147-3153 (1995). [PMID: 7852397]

[EC created 2006]