EC - Glycochenodeoxycholate sulfotransferase

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IntEnz Enzyme Nomenclature


Accepted name:
glycochenodeoxycholate sulfotransferase
Other names:
bile acid:3'-phosphoadenosine-5'-phosphosulfate sulfotransferase
bile acid:PAPS:sulfotransferase
Systematic name:
3'-phosphoadenylyl-sulfate:glycochenodeoxycholate 7-sulfotransferase



The enzyme specifically sulfates glycochenodeoxycholate at the 7α-position (see also EC bile-salt sulfotransferase). The monohydroxy bile acids glycolithocholate, chenodeoxycholate and ursodeoxycholate act as inhibitors.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , DIAGRAM , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
Gene Ontology: GO:0033876


  1. Barnes, S., Burhol, P.G., Zander, R., Haggstrom, G., Settine, R.L. and Hirschowitz, B.I.
    Enzymatic sulfation of glycochenodeoxycholic acid by tissue fractions from adult hamsters.
    J. Lipid Res. 20: 952-959 (1979). [PMID: 533830]
  2. Russell, D.W.
    The enzymes, regulation, and genetics of bile acid synthesis.
    Annu. Rev. Biochem. 72: 137-174 (2003). [PMID: 12543708]

[EC created 2005]