EC - Neoxanthin synthase

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IntEnz Enzyme Nomenclature


Accepted name:
neoxanthin synthase
Other name:
Systematic name:
violaxanthin—neoxanthin isomerase (epoxide-opening)



The opening of the epoxide ring of violaxanthin generates a chiral allene. Neoxanthin is a precursor of the plant hormone abscisic acid and the last product of carotenoid synthesis in green plants [2].

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , DIAGRAM , DIAGRAM , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
Gene Ontology: GO:0034020


  1. Al-Babili, S., Hugueney, P., Schledz, M., Welsch, R., Frohnmeyer, H., Laule, O. and Beyer, P.
    Identification of a novel gene coding for neoxanthin synthase from Solanum tuberosum.
    FEBS Lett. 485 : 168-172 (2000). [PMID: 11094161]
  2. Bouvier, F., d'Harlingue, A., Backhaus, R.A., Kumagai, M.H. and Camara, B.
    Identification of neoxanthin synthase as a carotenoid cyclase paralog.
    Eur. J. Biochem. 267 : 6346-6352 (2000). [PMID: 11029576]

[EC created 2005]