EC 2.1.1.20 - Glycine N-methyltransferase

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ENZYME: 2.1.1.20


ID   2.1.1.20
DE   Glycine N-methyltransferase.
AN   Glycine methyltransferase.
CA   S-adenosyl-L-methionine + glycine = S-adenosyl-L-homocysteine +
CA   sarcosine.
CC   -!- Thought to play an important role in the regulation of methyl group
CC       metabolism in the liver and pancreas by regulating the ratio between
CC       S-adenosyl-L-methionine and S-adenosyl-L-homocysteine.
CC   -!- Inhibited by 5-methyltetrahydrofolate pentaglutamate.
CC   -!- Sarcosine, which has no physiological role, is converted back into
CC       glycine by the action of EC 1.5.8.3.
DR   Q14749    , GNMT_HUMAN ;  Q9QXF8    , GNMT_MOUSE ;  Q29555    , GNMT_PIG   ;
DR   Q29513    , GNMT_RABIT ;  P13255    , GNMT_RAT   ;
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