EC 2.7.9.5 - Phosphoglucan, water dikinase

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IntEnz Enzyme Nomenclature
EC 2.7.9.5

Names

Accepted name:
phosphoglucan, water dikinase
Other names:
PWD
OK1
Systematic name:
ATP:phospho-α-glucan, water phosphotransferase

Reaction

Comments:

The enzyme phosphorylates granular starch that has previously been phosphorylated by EC 2.7.9.4, α-glucan, water dikinase; there is no activity with unphosphorylated glucans. It transfers the β-phosphate of ATP to the phosphoglucan, whereas the γ-phosphate is transferred to water [1]. In contrast to EC 2.7.9.4, which phosphorylates the glucose groups in glucans predominantly on O-6, this enzyme phosphorylates glucose groups in phosphorylated starch predominantly on O-3 [2]. The protein phosphorylates itself with the β-phosphate of ATP, which is then transferred to the glucan [1].

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
Gene Ontology: GO:0102217 , GO:0051752 , GO:0102219
CAS Registry Number: 912567-76-1
UniProtKB/Swiss-Prot:

References

  1. Kötting, O., Pusch, K., Tiessen, A., Geigenberger, P., Steup, M. and Ritte, G.
    Identification of a novel enzyme required for starch metabolism in Arabidopsis leaves. The phosphoglucan, water dikinase.
    Plant Physiol. 137: 242-252 (2005). [PMID: 15618411]
  2. Ritte, G., Heydenreich, M., Mahlow, S., Haebel, S., Kötting, O., Steup, M.
    Phosphorylation of C6- and C3-positions of glucosyl residues in starch is catalysed by distinct dikinases.
    FEBS Lett. 580: 4872-4876 (2006). [PMID: 16914145]

[EC 2.7.9.5 created 2005]