EC - Tabersonine 16-O-methyltransferase

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IntEnz Enzyme Nomenclature


Accepted name:
tabersonine 16-O-methyltransferase
Other names:
11-demethyl-17-deacetylvindoline 11-methyltransferase
11-O-demethyl-17-O-deacetylvindoline O-methyltransferase
S-adenosyl-L-methionine:11-O-demethyl-17-O-deacetylvindoline 11-O-methyltransferase
Systematic name:
S-adenosyl-L-methionine:16-hydroxytabersonine 16-O-methyltransferase



Involved in the biosynthesis of vindoline from tabersonine in the Madagascar periwinkle, Catharanthus roseus.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , DIAGRAM , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
Gene Ontology: GO:0030766
CAS Registry Number: 100984-95-0


  1. De Luca, V., Balsevich, J., Tyler, R.T., Eilert, U., Panchuk, B.D. and Kurz, W.G.W.
    Biosynthesis of indole alkaloids - developmental regulation of the biosynthetic-pathway from tabersonine to vindoline in Catharanthus roseus.
    J. Plant Physiol. 125 : 147-156 (1986).
  2. Fahn, W., Laussermair, E., Deus-Neumann, B. and Stöckigt, J.
    Late enzymes of vindoline biosynthesis. S-Adenosyl-L-methionine:11-O-demethyl-17-O-deacetylvindoline 11-O-methylase and unspecific acetylesterase.
    Plant Cell Rep. 4 : 337-340 (1985).

[EC created 1989, modified 2005]