EC 1.14.13.92 - Phenylacetone monooxygenase

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ENZYME: 1.14.13.92


ID   1.14.13.92
DE   Phenylacetone monooxygenase.
AN   PAMO.
CA   Phenylacetone + NADPH + O(2) = benzyl acetate + NADP(+) + H(2)O.
CF   FAD.
CC   -!- NADH cannot replace NADPH as coenzyme.
CC   -!- In addition to phenylacetone, which is the best substrate found to
CC       date, this Baeyer-Villiger monooxygenase can oxidize other aromatic
CC       ketones (1-(4-hydroxyphenyl)propan-2-one, 1-(4-hydroxyphenyl)propan-
CC       2-one and 3-phenylbutan-2-one), some alipatic ketones (e.g. dodecan-
CC       2-one) and sulfides (e.g. 1-methyl-4-(methylsulfanyl)benzene).
DR   Q47PU3    , PAMO_THEFY ;
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