EC - Pyranose oxidase

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IntEnz Enzyme Nomenclature


Accepted name:
pyranose oxidase
Other names:
glucose 2-oxidase
Systematic name:
pyranose:oxygen 2-oxidoreductase




A flavoprotein (FAD). Also oxidizes D-xylose, L-sorbose and D-glucono-1,5-lactone, which have the same ring conformation and configuration at C-2, C-3 and C-4.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
Gene Ontology: GO:0050233
CAS Registry Number: 37250-80-9


  1. Janssen, F.W. and Ruelius, H.W.
    Carbohydrate oxidase, a novel enzyme from Polyporus obtusus. II. Specificity and characterization of reaction products.
    Biochim. Biophys. Acta 167: 501-510 (1968). [PMID: 5722278]
  2. Machida, Y. and Nakanishi, T.
    Purification and properties of pyranose oxidase from Coriolus versicolor.
    Agric. Biol. Chem. 48: 2463-2470 (1984).
  3. Neidleman, S.L., Amon, W.F.,Jr. and Geigert, J.
    Fructose from glucose by enzymic conversion.
    U.S. Patent 4 246 347
  4. Ruelius, H.W., Kerwin, R.M. and Janssen, F.W.
    Carbohydrate oxidase, a novel enzyme from Polyporus obtusus. I. Isolation and purification.
    Biochim. Biophys. Acta 167: 493-500 (1968). [PMID: 5725162]

[EC created 1972]