EC 2.1.1.155 - Kaempferol 4'-O-methyltransferase

  IntEnz view ENZYME view

IntEnz Enzyme Nomenclature
EC 2.1.1.155

Names

Accepted name:
kaempferol 4'-O-methyltransferase
Other names:
S-adenosyl-L-methionine:flavonoid 4'-O-methyltransferase
F 4'-OMT
Systematic name:
S-adenosyl-L-methionine:kaempferol 4'-O-methyltransferase

Reaction

Comments:

The enzyme acts on the hydroxy group in the 4'-position of some flavones, flavanones and isoflavones. Kaempferol, apigenin and kaempferol triglucoside are substrates, as is genistein, which reacts more slowly. Compounds with an hydroxy group in the 3' and 4' positions, such as quercetin and eriodictyol, do not act as substrates. Similar to EC 2.1.1.75, apigenin 4'-O-methyltransferase and EC 2.1.1.83, 3,7-dimethylquercetin 4'-O-methyltransferase.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , DIAGRAM , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
Gene Ontology: GO:0033803

References

  1. Curir, P., Lanzotti, V., Dolci, M., Dolci, P., Pasini, C. and Tollin, G.
    Purification and properties of a new S-adenosyl-L-methionine:flavonoid 4'-O-methyltransferase from carnation (Dianthus caryophyllus L.).
    Eur. J. Biochem. 270: 3422-3431 (2003). [PMID: 12899699]

[EC 2.1.1.155 created 2004]