EC 3.8.1.10 - 2-haloacid dehalogenase (configuration-inverting)

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ENZYME: 3.8.1.10


ID   3.8.1.10
DE   2-haloacid dehalogenase (configuration-inverting).
AN   2-haloalkanoic acid dehalogenase.
AN   2-haloalkanoid acid halidohydrolase.
AN   DL-2-haloacid dehalogenase.
AN   DL-2-haloacid dehalogenase (inversion of configuration).
AN   DL-2-haloacid halidohydrolase (inversion of configuration).
AN   DL-DEXi.
CA   (1) (S)-2-haloacid + H(2)O = (R)-2-hydroxyacid + halide.
CA   (2) (R)-2-haloacid + H(2)O = (S)-2-hydroxyacid + halide.
CC   -!- Dehalogenates both (S)- and (R)-2-haloalkanoic acids to the
CC       corresponding (R)- and (S)-hydroxyalkanoic acids, respectively, with
CC       inversion of configuration at C-2.
CC   -!- The enzyme from Pseudomonas sp. 113 acts on 2-haloalkanoic acids
CC       whose carbon chain lengths are five or less (see also EC 3.8.1.2,
CC       EC 3.8.1.9 and EC 3.8.1.11).
DR   O06652    , HADDL_PSES4;  Q59168    , HDDL_ALCXX ;
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