EC 1 - Oxidoreductases
EC 1.1 - Acting on the CH-OH group of donors
EC 1.1.1 - With NAD+ or NADP+ as acceptor
EC 1.1.1.47 - Glucose 1-dehydrogenase [NAD(P)+]
IntEnz view
ENZYME view
IntEnz Enzyme Nomenclature
EC 1.1.1.47
Names
Accepted name:
glucose 1-dehydrogenase [NAD(P)+]
Other
names:
D-glucose dehydrogenase (NAD(P))
hexose phosphate dehydrogenase
hexose phosphate dehydrogenase
Systematic name:
D-glucose:NAD(P)+ 1-oxidoreductase
Reactions
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14405 [IUBMB]D-glucoseName origin: UniProt - CHECKED (C)Formula: C6H12O6
Charge: 0ChEBI compound status: CHECKED (C)NADP+Name origin: UniProt - CHECKED (C)Formula: C21H25N7O17P3
Charge: -3ChEBI compound status: CHECKED (C)=D-glucono-1,5-lactoneName origin: UniProt - CHECKED (C)Formula: C6H10O6
Charge: 0ChEBI compound status: CHECKED (C)H+Name origin: UniProt - CHECKED (C)Formula: H
Charge: 1ChEBI compound status: CHECKED (C) -
14293 [IUBMB]D-glucoseName origin: UniProt - CHECKED (C)Formula: C6H12O6
Charge: 0ChEBI compound status: CHECKED (C)NAD+Name origin: UniProt - CHECKED (C)Formula: C21H26N7O14P2
Charge: -1ChEBI compound status: CHECKED (C)=D-glucono-1,5-lactoneName origin: UniProt - CHECKED (C)Formula: C6H10O6
Charge: 0ChEBI compound status: CHECKED (C)H+Name origin: UniProt - CHECKED (C)Formula: H
Charge: 1ChEBI compound status: CHECKED (C)
Comments:
This enzyme has similar activity with either NAD+ or NADP+. cf. EC 1.1.1.118, glucose 1-dehydrogenase (NAD+) and EC 1.1.1.119, glucose 1-dehydrogenase (NADP+).
Links to other databases
Enzymes and pathways:
NC-IUBMB
,
BRENDA
,
ExplorEnz
,
ENZYME@ExPASy
,
KEGG
,
MetaCyc
,
NIST 74
,
UniPathway
Protein domains and families:
PROSITE:PDOC00060
,
PROSITE:PDOC00067
Gene Ontology:
GO:0047936
CAS Registry Number:
9028-53-9
References
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A glucose dehydrogenase for the determination of glucose concentrations in body fluids.Z. Klin. Chem. Klin. Biochem. 13 : 101-107 (1975). [PMID: 810982]
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Beef liver glucose dehydrogenase. 1. Purification and properties.Acta Chem. Scand. 7 : 1081-1089 (1953).
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D-Glucose dehydrogenase from Bacillus megaterium M 1286: purification, properties and structure.Hoppe-Seyler's Z. Physiol. Chem. 356 : 1613-1623 (1975). [PMID: 2530]
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Glucose dehydrogenase.J. Biol. Chem. 196 : 769-784 (1952). [PMID: 12981017]
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Glucose dehydrogenase from pig liver. I. Isolation and purification.Biochim. Biophys. Acta 198 : 397-406 (1970). [PMID: 4392298]
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Location and properties of glucose dehydrogenase in sporulating cells and spores of Bacillus subtilis.J. Bacteriol. 132 : 282-293 (1977). [PMID: 21162]
[EC 1.1.1.47 created 1961, modified 2013]