EC - Glucose 1-dehydrogenase [NAD(P)+]

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IntEnz Enzyme Nomenclature


Accepted name:
glucose 1-dehydrogenase [NAD(P)+]
Other names:
D-glucose dehydrogenase (NAD(P))
hexose phosphate dehydrogenase
Systematic name:
D-glucose:NAD(P)+ 1-oxidoreductase



This enzyme has similar activity with either NAD+ or NADP+. cf. EC, glucose 1-dehydrogenase (NAD+) and EC, glucose 1-dehydrogenase (NADP+).

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , NIST 74 , UniPathway
Protein domains and families: PROSITE:PDOC00060 , PROSITE:PDOC00067
Structural data: CSA , EC2PDB
Gene Ontology: GO:0047936
CAS Registry Number: 9028-53-9
UniProtKB/Swiss-Prot: (32) [show] [UniProt]


  1. Banauch, D., Brummer, W., Ebeling, W., Metz, H., Rindfrey, H., Lang, H., Leybold, K. and Rick, W.
    A glucose dehydrogenase for the determination of glucose concentrations in body fluids.
    Z. Klin. Chem. Klin. Biochem. 13 : 101-107 (1975). [PMID: 810982]
  2. Brink, N.G.
    Beef liver glucose dehydrogenase. 1. Purification and properties.
    Acta Chem. Scand. 7 : 1081-1089 (1953).
  3. Pauly, H.E. and Pfleiderer, G.
    D-Glucose dehydrogenase from Bacillus megaterium M 1286: purification, properties and structure.
    Hoppe-Seyler's Z. Physiol. Chem. 356 : 1613-1623 (1975). [PMID: 2530]
  4. Strecker, H.J. and Korkes, S.
    Glucose dehydrogenase.
    J. Biol. Chem. 196 : 769-784 (1952). [PMID: 12981017]
  5. Thompson, R.E. and Carper, W.R.
    Glucose dehydrogenase from pig liver. I. Isolation and purification.
    Biochim. Biophys. Acta 198 : 397-406 (1970). [PMID: 4392298]
  6. Fujita, Y., Ramaley, R., Freese, E.
    Location and properties of glucose dehydrogenase in sporulating cells and spores of Bacillus subtilis.
    J. Bacteriol. 132 : 282-293 (1977). [PMID: 21162]

[EC created 1961, modified 2013]