EC 2.3.1.162 - Taxadien-5α-ol O-acetyltransferase

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ENZYME: 2.3.1.162


ID   2.3.1.162
DE   Taxadien-5-alpha-ol O-acetyltransferase.
AN   Taxa-4(20),11(12)-dien-5-alpha-ol O-acetyltransferase.
AN   Taxadienol acetyltransferase.
CA   Acetyl-CoA + taxa-4(20),11-dien-5-alpha-ol = CoA + taxa-4(20),11-dien-5-
CA   alpha-yl acetate.
CC   -!- This is the third enzyme in the biosynthesis of the diterpenoid
CC       antineoplastic drug taxol (paclitaxel), which is widely used in the
CC       treatment of carcinomas, sarcomas and melanomas.
DR   Q9M6F0    , T5AT_TAXCU ;  Q8S9G6    , T5AT_TAXWC ;
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