EC - Bacterial ABC-type protein transporter

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IntEnz Enzyme Nomenclature


Accepted name:
bacterial ABC-type protein transporter
Other name:
peptide-transporting ATPase [ambiguous]
Systematic name:
ATP phosphohydrolase (ABC-type, peptide-exporting)



An ATP-binding cassette (ABC) type transporter, characterized by the presence of two similar ATP-binding domains/proteins and two integral membrane domains/proteins. This entry stands for a family of bacterial enzymes that are dedicated to the secretion of one or several closely related proteins belonging to the toxin, protease and lipase families. Examples from Gram-negative bacteria include α-hemolysin, cyclolysin, colicin V and siderophores, while examples from Gram-positive bacteria include bacteriocin, subtilin, competence factor and pediocin. Formerly EC

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Protein domains and families: PROSITE:PDOC00185 , PROSITE:PDOC50990
Structural data: CSA , EC2PDB
Gene Ontology: GO:0015440
UniProtKB/Swiss-Prot: (13) [show] [UniProt]


  1. Klein, C. and Entian, K.D.
    Genes involved in self-protection against the lantibiotic subtilin produced by Bacillus subtilis ATCC 6633.
    Appl. Environ. Microbiol. 60 : 2793-2801 (1994). [PMID: 8085823]
  2. Binet, R., Létoffé, S., Ghigo, J.M., Delepaire, P. and Wanderman, C.
    Protein secretion by Gram-negative bacterial ABC exporters - a review.
    Gene 192 : 7-11 (1997). [PMID: 9224868]
  3. Letoffe, S., Delepelaire, P., Wandersman, C.
    Protease secretion by Erwinia chrysanthemi: the specific secretion functions are analogous to those of Escherichia coli alpha-haemolysin.
    EMBO J. 9 : 1375-1382 (1990). [PMID: 2184029]

[EC created 2000 as EC, transferred 2018 to EC]