EC 6 - Ligases
EC 6.3 - Forming carbon-nitrogen bonds
EC 6.3.5 - Carbon—nitrogen ligases with glutamine as amido-N-donor
EC 6.3.5.3 - Phosphoribosylformylglycinamidine synthase
IntEnz view
ENZYME view
IntEnz Enzyme Nomenclature
EC 6.3.5.3
Names
Accepted name:
phosphoribosylformylglycinamidine synthase
Other
names:
FGAM synthetase
FGAR amidotransferase
formylglycinamide ribonucloetide amidotransferase
phosphoribosylformylglycinamidine synthetase
phosphoribosylformylglycineamidine synthetase
formylglycinamide ribotide amidotransferase
FGARAT
FGAM synthase
5'-phosphoribosylformylglycinamide:L-glutamine amido-ligase (ADP-forming)
2-N-formyl-1-N-(5-phospho-D-ribosyl)glycinamide:L-glutamine amido-ligase (ADP-forming)
FGAR amidotransferase
formylglycinamide ribonucloetide amidotransferase
phosphoribosylformylglycinamidine synthetase
phosphoribosylformylglycineamidine synthetase
formylglycinamide ribotide amidotransferase
FGARAT
FGAM synthase
5'-phosphoribosylformylglycinamide:L-glutamine amido-ligase (ADP-forming)
2-N-formyl-1-N-(5-phospho-D-ribosyl)glycinamide:L-glutamine amido-ligase (ADP-forming)
Systematic name:
N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide:L-glutamine amido-ligase (ADP-forming)
Reaction
-
17129 [IUBMB]+ATPName origin: UniProt - CHECKED (C)Formula: C10H12N5O13P3
Charge: -4ChEBI compound status: CHECKED (C)+H2OName origin: UniProt - CHECKED (C)Formula: H2O
Charge: 0ChEBI compound status: CHECKED (C)+L-glutamineName origin: UniProt - CHECKED (C)Formula: C5H10N2O3
Charge: 0ChEBI compound status: CHECKED (C)N2-formyl-N1-(5-phospho-D-ribosyl)glycinamideName origin: UniProt - CHECKED (C)Formula: C8H13N2O9P
Charge: -2ChEBI compound status: CHECKED (C)=+2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidineName origin: UniProt - CHECKED (C)Formula: C8H15N3O8P
Charge: -1ChEBI compound status: CHECKED (C)+ADPName origin: UniProt - CHECKED (C)Formula: C10H12N5O10P2
Charge: -3ChEBI compound status: CHECKED (C)+H+Name origin: UniProt - CHECKED (C)Formula: H
Charge: 1ChEBI compound status: CHECKED (C)+L-glutamateName origin: UniProt - CHECKED (C)Formula: C5H8NO4
Charge: -1ChEBI compound status: CHECKED (C)
Links to other databases
Enzymes and pathways:
NC-IUBMB
,
BRENDA
,
DIAGRAM
,
ExplorEnz
,
ENZYME@ExPASy
,
KEGG
,
MetaCyc
,
UniPathway
Protein domains and families:
PROSITE:PDOC00405
Gene Ontology:
GO:0004642
CAS Registry Number:
9032-84-2
References
-
Biosynthesis of the purines. XIV. Conversion of (α-N-formyl)glycinamide ribotide to (α-N-formyl)glycinamidine ribotide; purification and requirements of the enzyme system.J. Biol. Chem. 225: 157-162 (1957). [PMID: 13416226]
[EC 6.3.5.3 created 1961, modified 2000]