EC - NAD+ synthase (glutamine-hydrolysing)

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IntEnz Enzyme Nomenclature


Accepted name:
NAD+ synthase (glutamine-hydrolysing)
Other names:
DPN synthetase
NAD synthetase (glutamine-hydrolysing)
desamidonicotinamide adenine dinucleotide amidotransferase
nicotinamide adenine dinucleotide synthetase (glutamine)
NAD+ synthetase (glutamine-hydrolyzing)
Systematic name:
deamido-NAD+:L-glutamine amido-ligase (AMP-forming)



NH3 can act instead of glutamine (cf. EC NAD+ synthase).

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Protein domains and families: PROSITE:PDOC50263
Structural data: CSA , EC2PDB
Gene Ontology: GO:0003952
CAS Registry Number: 37318-70-0
UniProtKB/Swiss-Prot: (25) [show] [UniProt]


  1. Imsande, J.
    Pathway of diphosphopyridine nucleotide biosynthesis in Escherichia coli.
    J. Biol. Chem. 236 : 1494-1497 (1961).
  2. Imsande, J. and Handler, P.
    Biosynthesis of diphosphopyridine nucleotide. III. Nicotinic acid mononucleotide pyrophosphorylase.
    J. Biol. Chem. 236 : 525-530 (1961).

[EC created 1961]