EC - Dethiobiotin synthase

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IntEnz Enzyme Nomenclature


Accepted name:
dethiobiotin synthase
Other name:
desthiobiotin synthase
Systematic name:
7,8-diaminononanoate:carbon-dioxide cyclo-ligase (ADP-forming)



CTP has half the activity of ATP.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ERGO , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
Gene Ontology: GO:0004141
CAS Registry Number: 37259-75-9
UniProtKB/Swiss-Prot: (262) [show] [UniProt]


  1. Krell, K. and Eisenberg, M.A.
    The purification and properties of dethiobiotin synthetase.
    J. Biol. Chem. 245 : 6558-6566 (1970). [PMID: 4921568]
  2. Yang, H.-C., Tani, Y. and Ogata, K.
    Synthesis of biotin vitamers from biotin diaminocarboxylic acid or 7,8-diaminopelargonic acid by a purified enzyme of Pseudomonas graveolens.
    Agric. Biol. Chem. 34 : 1748-1750 (1970).

[EC created 1976]