EC - NAD+ synthase

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IntEnz Enzyme Nomenclature


Accepted name:
NAD+ synthase
Other names:
NAD synthetase
NAD+ synthetase
diphosphopyridine nucleotide synthetase
nicotinamide adenine dinucleotide synthetase
Systematic name:
deamido-NAD+:ammonia ligase (AMP-forming)



L-Glutamine also acts, more slowly, as amido-donor [cf. EC NAD+ synthase (glutamine-hydrolysing)].

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
Gene Ontology: GO:0008795
CAS Registry Number: 9032-69-3
UniProtKB/Swiss-Prot: (291) [show] [UniProt]


  1. Spencer, R.L. and Preiss, J.
    Biosynthesis of diphosphopyridine nucleotide. The purification and the properties of diphosphopyridine nucleotide synthetase from Escherichia coli B.
    J. Biol. Chem. 242 : 385-392 (1967). [PMID: 4290215]

[EC created 1972]