EC 6 - Ligases
EC 6.3 - Forming carbon-nitrogen bonds
EC 6.3.1 - Acid—ammonia (or amine) ligases (amide synthases)
EC 6.3.1.1 - Aspartate—ammonia ligase
IntEnz view
ENZYME view
IntEnz Enzyme Nomenclature
EC 6.3.1.1
Names
Accepted name:
aspartate—ammonia ligase
Other
names:
L-asparagine synthetase
asparagine synthetase
asparagine synthetase
Systematic name:
L-aspartate:ammonia ligase (AMP-forming)
Reaction
- ATP + L-aspartate + NH3 = AMP + diphosphate + L-asparagine
Links to other databases
Enzymes and pathways:
NC-IUBMB
,
BRENDA
,
ERGO
,
ExplorEnz
,
ENZYME@ExPASy
,
KEGG
,
MetaCyc
,
UniPathway
Gene Ontology:
GO:0004071
CAS Registry Number:
9023-69-2
References
-
Asparagine biosynthesis in Lactobacillus arabinosusand its control by asparagine through enzyme inhibition and repression.J. Biol. Chem. 237 : 2845-2849 (1962).
-
Aspartate metabolism and asparagine synthesis in plant systems.J. Biol. Chem. 215 : 91-99 (1955).
[EC 6.3.1.1 created 1961]