EC - 4-chlorobenzoate—CoA ligase

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IntEnz Enzyme Nomenclature


Accepted name:
4-chlorobenzoate—CoA ligase
Systematic name:
4-chlorobenzoate:CoA ligase




requires Mg2+. This enzyme is part of the bacterial 2,4-dichlorobenzoate degradation pathway.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UM-BBD , UniPathway
Structural data: CSA , EC2PDB
Gene Ontology: GO:0018861


  1. Dunaway-Mariano, D., Babbitt, P.C.
    On the origins and functions of the enzymes of the 4-chlorobenzoate to 4-hydroxybenzoate converting pathway.
    Biodegradation 5 : 259-276 (1994). [PMID: 7765837]
  2. Loffler, F., Muller, R., Lingens, F.
    Purification and properties of 4-halobenzoate-coenzyme A ligase from Pseudomonas sp. CBS3.
    Biol. Chem. Hoppe-Seyler 373 : 1001-1007 (1992). [PMID: 1418673]
  3. Chang, K.H., Liang, P.H., Beck, W., Scholten, J.D., Dunaway-Mariano, D.
    Isolation and characterization of the three polypeptide components of 4-chlorobenzoate dehalogenase from Pseudomonas sp. strain CBS-3.
    Biochemistry 31 : 5605-5610 (1992). [PMID: 1610806]

[EC created 1999]