EC - Citrate—CoA ligase

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IntEnz Enzyme Nomenclature


Accepted name:
citrate—CoA ligase
Other names:
citrate thiokinase
citrate:CoA ligase
citryl-CoA synthetase
Systematic name:
citrate:CoA ligase (ADP-forming)



The enzyme is a component of EC ATP citrate (pro-S)-lyase.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
Gene Ontology: GO:0047779
CAS Registry Number: 856428-87-0


  1. Lill, U., Schreil, A. and Eggerer, H.
    Isolation of enzymically active fragments formed by limited proteolysis of ATP citrate lyase.
    Eur. J. Biochem. 125: 645-650 (1982). [PMID: 6749502]
  2. Aoshima, M., Ishii, M. and Igarashi, Y.
    A novel enzyme, citryl-CoA synthetase, catalysing the first step of the citrate cleavage reaction in Hydrogenobacter thermophilus TK-6.
    Mol. Microbiol. 52: 751-761 (2004). [PMID: 15101981]

[EC created 1986]