EC - 6-carboxyhexanoate—CoA ligase

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IntEnz Enzyme Nomenclature


Accepted name:
6-carboxyhexanoate—CoA ligase
Other names:
6-carboxyhexanoyl-CoA synthetase
pimelyl-CoA synthetase
Systematic name:
6-carboxyhexanoate:CoA ligase (AMP-forming)


Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ERGO , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
Gene Ontology: GO:0042410
CAS Registry Number: 55467-50-0
UniProtKB/Swiss-Prot: (52) [show] [UniProt]


  1. Izumi, Y., Morita, H., Sato, K., Tani, Y. and Ogata, K.
    Synthesis of biotin-vitamers from pimelic acid and coenzyme A by cell-free extracts of various bacteria.
    Biochim. Biophys. Acta 264 : 210-213 (1972). [PMID: 4623286]
  2. Izumi, Y., Morita, H., Tani, Y. and Ogata, K.
    The pimelyl-CoA synthetase responsible for the first step in biotin biosynthesis by microorganisms.
    Agric. Biol. Chem. 38 : 2257-2262 (1974).

[EC created 1983]