EC 6.2.1.13 - Acetate—CoA ligase (ADP-forming)
IntEnz view
ENZYME view
IntEnz Enzyme Nomenclature
EC 6.2.1.13
Names
Accepted name:
acetate—CoA ligase (ADP-forming)
Other
names:
acetate thiokinase
acetyl coenzyme A synthetase (adenosine diphosphate-forming)
acetyl-CoA synthetase (ADP-forming)
acetyl coenzyme A synthetase (adenosine diphosphate-forming)
acetyl-CoA synthetase (ADP-forming)
Systematic name:
acetate:CoA ligase (ADP-forming)
Reaction
- ATP + acetate + CoA = ADP + phosphate + acetyl-CoA
Comments:
Also acts on propanoate and, very slowly, on butanoate.
Links to other databases
Enzymes and pathways:
NC-IUBMB
,
BRENDA
,
ERGO
,
ExplorEnz
,
ENZYME@ExPASy
,
KEGG
,
MetaCyc
,
UniPathway
Gene Ontology:
GO:0043758
CAS Registry Number:
62009-85-2
UniProtKB/Swiss-Prot:
ACD1_ARCFU
ACD2_ARCFU
ACDA1_PYRFU
ACDA2_PYRFU
ACDB1_PYRFU
ACDB2_PYRFU
ACD_METJA
PPSA_ASPOR
References
-
An energy-conserving pyruvate-to-acetate pathway in Entamoeba histolytica. Pyruvate synthase and a new acetate thiokinase.J. Biol. Chem. 252 : 726-731 (1977). [PMID: 13076]
[EC 6.2.1.13 created 1978]