EC - Alanine—tRNA ligase

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IntEnz Enzyme Nomenclature


Accepted name:
alanine—tRNA ligase
Other names:
Ala-tRNA synthetase
alanine tRNA synthetase
alanine transfer RNA synthetase
alanine translase
alanine-transfer RNA ligase
alanyl-tRNA synthetase
alanyl-transfer RNA synthetase
alanyl-transfer ribonucleate synthase
alanyl-transfer ribonucleate synthetase
alanyl-transfer ribonucleic acid synthetase
Systematic name:
L-alanine:tRNAAla ligase (AMP-forming)


Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ERGO , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Protein domains and families: PROSITE:PDOC00363
Structural data: CSA , EC2PDB
Gene Ontology: GO:0004813
CAS Registry Number: 9031-71-4
UniProtKB/Swiss-Prot: (721) [show] [UniProt]


  1. Holley, R.W. and Goldstein, J.
    An alanine-dependent, ribonuclease-inhibited conversion of adenosine 5'-phosphate to adenosine triphosphate.
    J. Biol. Chem. 234 : 1765-1768 (1959).
  2. Webster, G.C.
    Isolation of an alanine-activating enzyme from pig liver.
    Biochim. Biophys. Acta 49 : 141-152 (1961).

[EC created 1961]