EC - Tryptophan—tRNA ligase

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IntEnz Enzyme Nomenclature


Accepted name:
tryptophan—tRNA ligase
Other names:
L-tryptophan-tRNATrp ligase (AMP-forming)
tryptophan translase
tryptophanyl ribonucleic synthetase
tryptophanyl-tRNA synthase
tryptophanyl-tRNA synthetase
tryptophanyl-transfer RNA synthetase
tryptophanyl-transfer ribonucleate synthetase
tryptophanyl-transfer ribonucleic acid synthetase
tryptophanyl-transfer ribonucleic synthetase
Systematic name:
L-tryptophan:tRNATrp ligase (AMP-forming)


Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Protein domains and families: PROSITE:PDOC00161
Structural data: CSA , EC2PDB
Gene Ontology: GO:0004830
CAS Registry Number: 9023-44-3
UniProtKB/Swiss-Prot: (173) [show] [UniProt]


  1. Davie, E.W., Koningsberger, V.V. and Lipmann, F.
    The isolation of a tryptophan-activating enzyme from pancreas.
    Arch. Biochem. Biophys. 65 : 21-28 (1956).
  2. Preddie, E.C.
    Tryptophanyl transfer ribonucleic acid synthetase from bovine pancreas. II. The chemically different subunits.
    J. Biol. Chem. 244 : 3958-3968 (1969). [PMID: 5805407]
  3. Wong, K.K., Meister, A. and Moldave, K.
    Enzymic formation of ribonucleic acid-amino acid from synthetic aminoacyladenylate and ribonucleic acid.
    Biochim. Biophys. Acta 36 : 531-533 (1959).

[EC created 1961, modified 2002]