EC 6 - Ligases


Ligases are enzymes that catalyse the joining of two molecules with concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate. 'Ligase' is commonly used for the common name, but, in a few cases, 'synthase' or 'carboxylase' is used. 'Synthetase' may be used in place of 'synthase' for enzymes in this class.


EC 6.1
Forming carbon-oxygen bonds
EC 6.2
Forming carbon-sulfur bonds
EC 6.3
Forming carbon-nitrogen bonds
EC 6.4
Forming carbon-carbon bonds
EC 6.5
Forming phosphoric ester bonds
EC 6.6
Forming nitrogen-metal bonds