EC - Lanosterol synthase

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IntEnz Enzyme Nomenclature


Accepted name:
lanosterol synthase
Other names:
2,3-epoxysqualene lanosterol cyclase
2,3-oxidosqualene cyclase
2,3-oxidosqualene sterol cyclase
2,3-oxidosqualene—lanosterol cyclase
lanosterol 2,3-oxidosqualene cyclase
oxidosqualene cyclase
oxidosqualene—lanosterol cyclase
squalene 2,3-epoxide:lanosterol cyclase
squalene epoxidase-cyclase
squalene-2,3-oxide-lanosterol cyclase
2,3-epoxysqualene--lanosterol cyclase
(S)-2,3-epoxysqualene mutase (cyclizing, lanosterol-forming)
Systematic name:
(3S)-2,3-epoxy-2,3-dihydrosqualene mutase (cyclizing, lanosterol-forming)


Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , DIAGRAM , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Protein domains and families: PROSITE:PDOC00825
Structural data: CSA , EC2PDB
Gene Ontology: GO:0000250
CAS Registry Number: 9032-71-7
UniProtKB/Swiss-Prot: (15) [show] [UniProt]


  1. Dean, P.D.G., Oritz de Montellano, P.R., Bloch, K. and Corey, E.J.
    A soluble 2,3-oxidosqualene sterol cyclase.
    J. Biol. Chem. 242 : 3014-3015 (1967). [PMID: 6027261]

[EC created 1961 as EC, transferred 1965 to EC, part transferred 1972 to EC rest to EC]