EC 5.4.3.9 - Glutamate 2,3-aminomutase

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IntEnz Enzyme Nomenclature
EC 5.4.3.9

Names

Accepted name:
glutamate 2,3-aminomutase
Systematic name:
L-glutamate 2,3-aminomutase

Reaction

Cofactors

Comments:

This enzyme is a member of the 'AdoMet radical' (radical SAM) family. It contains pyridoxal phosphate and a [4Fe-4S] cluster, which is coordinated by 3 cysteines and binds an exchangeable S-adenosyl-L-methionine molecule. During the reaction cycle, the AdoMet forms a 5'-deoxyadenosyl radical, which is regenerated at the end of the reaction.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
UniProtKB/Swiss-Prot:

References

  1. Ruzicka, F. J., Frey, P. A.
    Glutamate 2,3-aminomutase: a new member of the radical SAM superfamily of enzymes.
    Biochim. Biophys. Acta 1774: 286-296 (2007). [PMID: 17222594]

[EC 5.4.3.9 created 2012]