EC 5.4.2.9 - Phosphoenolpyruvate mutase

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IntEnz Enzyme Nomenclature
EC 5.4.2.9

Names

Accepted name:
phosphoenolpyruvate mutase
Other names:
PEP phosphomutase
PEPPM
phosphoenolpyruvate phosphomutase
phosphoenolpyruvate-phosphonopyruvate phosphomutase
PEP mutase
Systematic name:
phosphoenolpyruvate 2,3-phosphonomutase

Reaction

Comments:

Involved in the biosynthesis of the C-P bond, although the equilibrium greatly favours phosphoenolpyruvate.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , DIAGRAM , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
Gene Ontology: GO:0050188
UniProtKB/Swiss-Prot:

References

  1. Bowman, E., McQueney, M., Barry, R.J. and Dunaway-Mariano, D.
    Catalysis and thermodynamics of the phosphoenolpyruvate phosphonopyruvate rearrangement - entry into the phosphonate class of naturally-occurring organo-phosphorus compounds
    . J. Am. Chem. Soc. 110: 5575-5576 (1988).
  2. Hikada, T., Imai, S., Hara, O., Anzai, H., Murakami, T., Nagaoka, K. and Seto, H.
    Carboxyphosphonoenolpyruvate phosphonomutase, a novel enzyme catalyzing C-P bond formation.
    J. Bacteriol. 172: 3066-3072 (1990). [PMID: 2160937]
  3. Seidel, H.M., Freeman, S. and Knowles, J.R.
    Phosphonate biosynthesis: isolation of the enzyme responsible for the formation of a carbon-phosphorus bond.
    Nature 335: 457-458 (1988). [PMID: 3138545]

[EC 5.4.2.9 created 1990]