EC 5.3.3.6 - Methylitaconate Δ-isomerase

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IntEnz Enzyme Nomenclature
EC 5.3.3.6

Names

Accepted name:
methylitaconate Δ-isomerase
Other name:
methylitaconate isomerase
Systematic name:
methylitaconate Δ23-isomerase

Reaction

Comments:

Forms part of the nicotinate-fermentation catabolism pathway in Eubacterium barkeri. Other enzymes involved in this pathway are EC 1.17.1.5 (nicotinate dehydrogenase), EC 1.3.7.1 (6-hydroxynicotinate reductase), EC 3.5.2.18 (enamidase), EC 1.1.1.291 (2-hydroxymethylglutarate dehydrogenase), EC 5.4.99.4 (2-methyleneglutarate mutase), EC 4.2.1.85 (dimethylmaleate hydratase) and EC 4.1.3.32 (2,3-dimethylmalate lyase).

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , DIAGRAM , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , NIST 74 , UniPathway
Structural data: CSA , EC2PDB
Gene Ontology: GO:0050100
CAS Registry Number: 9059-08-9
UniProtKB/Swiss-Prot:

References

  1. Kung, H.-F. and Stadtman, T.C.
    Nicotinic acid metabolism. VI. Purification and properties of α-methyleneglutarate mutase (B12-dependent) and methylitaconate isomerase.
    J. Biol. Chem. 246: 3378-3388 (1971). [PMID: 5574401]

[EC 5.3.3.6 created 1972]