EC 5 - Isomerases
EC 5.3 - Intramolecular oxidoreductases
EC 5.3.1 - Interconverting aldoses and ketoses
EC 5.3.1.8 - Mannose-6-phosphate isomerase
IntEnz view
ENZYME view
IntEnz Enzyme Nomenclature
EC 5.3.1.8
Names
Accepted name:
mannose-6-phosphate isomerase
Other
names:
D-mannose-6-phosphate ketol-isomerase
mannose phosphate isomerase
phosphohexoisomerase
phosphohexomutase
phosphomannoisomerase
phosphomannose isomerase
mannose phosphate isomerase
phosphohexoisomerase
phosphohexomutase
phosphomannoisomerase
phosphomannose isomerase
Systematic name:
D-mannose-6-phosphate aldose-ketose-isomerase
Reaction
- D-mannose 6-phosphate = D-fructose 6-phosphate
Cofactor
Comments:
A zinc protein.
Links to other databases
Enzymes and pathways:
NC-IUBMB
,
BRENDA
,
DIAGRAM
,
ExplorEnz
,
ENZYME@ExPASy
,
KEGG
,
MetaCyc
,
NIST 74
,
UniPathway
Protein domains and families:
PROSITE:PDOC00746
Gene Ontology:
GO:0004476
CAS Registry Number:
9023-88-5
References
-
Phosphomannose-isomerase. I. Über die Aktivitätsmessung und die Sulfhydryl-sowie die metallabhängigkeit der Enzymirkung in einigen Tierischen Geweben.Biochem. Z. 330 : 411-420 (1958). [PMID: 13596383]
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Studies on phosphomannose isomerase. II. Characterization as a zinc metalloenzyme.J. Biol. Chem. 243 : 4109-4116 (1968). [PMID: 4969968]
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Phosphomannose isomerase.J. Biol. Chem. 186 : 753-761 (1950). [PMID: 14794671]
[EC 5.3.1.8 created 1961, modified 1976]