EC - 5-dehydro-4-deoxy-D-glucuronate isomerase

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IntEnz Enzyme Nomenclature


Accepted name:
5-dehydro-4-deoxy-D-glucuronate isomerase
Other names:
4-deoxy-L-threo-5-hexulose uronate isomerase
5-keto-4-deoxyuronate isomerase
4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase
kduI (gene name)
Systematic name:
5-dehydro-4-deoxy-D-glucuronate aldose-ketose-isomerase



The enzyme is involved in the degradation of polygalacturonate, a later stage in the degradation of pectin by many microorganisms.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
Gene Ontology: GO:0008697
CAS Registry Number: 37318-44-8
UniProtKB/Swiss-Prot: (93) [show] [UniProt]


  1. Preiss, J.
    4-Deoxy-L-threo-5-hexosulose uronic acid isomerase.
    Methods Enzymol. 9 : 602-604 (1966).
  2. Condemine, G., Robert-Baudouy, J.
    Analysis of an Erwinia chrysanthemi gene cluster involved in pectin degradation.
    Mol. Microbiol. 5 : 2191-2202 (1991). [PMID: 1766386]
  3. Dunten, P., Jaffe, H., Aksamit, R. R.
    Crystallization of 5-keto-4-deoxyuronate isomerase from Escherichia coli.
    Acta Crystallogr. D Biol. Crystallogr. 54 : 678-680 (1998). [PMID: 9761873]
  4. Crowther, R. L., Georgiadis, M. M.
    The crystal structure of 5-keto-4-deoxyuronate isomerase from Escherichia coli.
    Proteins 61 : 680-684 (2005). [PMID: 16152643]

[EC created 1972, modified 2012]