EC 5.1.3.28 - UDP-N-acetyl-L-fucosamine synthase

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IntEnz Enzyme Nomenclature
EC 5.1.3.28

Names

Accepted name:
UDP-N-acetyl-L-fucosamine synthase
Other names:
WbjD
Cap5G
Systematic name:
UDP-2-acetamido-2,6-dideoxy-β-L-talose 2-epimerase

Reaction

Comments:

Isolated from the bacteria Pseudomonas aeruginosa and Staphylococcus aureus. Involved in bacterial polysaccharide biosynthesis.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB

References

  1. Kneidinger, B., O'Riordan, K., Li, J., Brisson, J. R., Lee, J. C., Lam, J. S.
    Three highly conserved proteins catalyze the conversion of UDP-N-acetyl-D-glucosamine to precursors for the biosynthesis of O antigen in Pseudomonas aeruginosa O11 and capsule in Staphylococcus aureus type 5. Implications for the UDP-N-acetyl-L-fucosamine biosynthetic pathway.
    J. Biol. Chem. 278: 3615-3627 (2003). [PMID: 12464616]
  2. Mulrooney, E. F., Poon, K. K., McNally, D. J., Brisson, J. R., Lam, J. S.
    Biosynthesis of UDP-N-acetyl-L-fucosamine, a precursor to the biosynthesis of lipopolysaccharide in Pseudomonas aeruginosa serotype O11.
    J. Biol. Chem. 280: 19535-19542 (2005). [PMID: 15778500]

[EC 5.1.3.28 created 2014]