EC - Ribulose-phosphate 3-epimerase

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IntEnz Enzyme Nomenclature


Accepted name:
ribulose-phosphate 3-epimerase
Other names:
D-ribulose 5-phosphate epimerase
D-ribulose phosphate-3-epimerase
D-ribulose-5-P 3-epimerase
D-xylulose-5-phosphate 3-epimerase
erythrose-4-phosphate isomerase
pentose-5-phosphate 3-epimerase
phosphoketopentose 3-epimerase
phosphoketopentose epimerase
phosphoribulose epimerase
ribulose 5-phosphate 3-epimerase
xylulose phosphate 3-epimerase
Systematic name:
D-ribulose-5-phosphate 3-epimerase



The enzyme also converts D-erythrose 4-phosphate into D-erythrulose 4-phosphate and D-threose 4-phosphate.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , DIAGRAM , DIAGRAM , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , NIST 74 , UniPathway
Protein domains and families: PROSITE:PDOC00833
Structural data: CSA , EC2PDB
Gene Ontology: GO:0004750
CAS Registry Number: 9024-20-8
UniProtKB/Swiss-Prot: (44) [show] [UniProt]


  1. Ashwell, G. and Hickman, J.
    Enzymatic formation of xylulose 5-phosphate from ribose 5-phosphate in spleen.
    J. Biol. Chem. 226: 65-76 (1957).
  2. Dickens, F. and Williamson, D.H.
    Pentose phosphate isomerase and epimerase from animal tissues.
    Biochem. J. 64: 567-578 (1956).
  3. Hurwitz, J. and Horecker, B.L.
    The purification of phosphoketopentoepimerase from Lactobacillus pentosus and the preparation of xylulose 5-phosphate.
    J. Biol. Chem. 223: 993-1008 (1956).
  4. Stumpf, P.K. and Horecker, B.L.
    The rôle of xylulose 5-phosphate in xylose metabolism of Lactobacillus pentosus.
    J. Biol. Chem. 218: 753-768 (1956).
  5. Terada, H., Mukae, K., Hosomi, S., Mizoguchi, T. and Uehara, K.
    Characterization of an enzyme which catalyzes isomerization and epimerization of D-erythrose 4-phosphate.
    Eur. J. Biochem. 148: 345-351 (1985). [PMID: 3987693]

[EC created 1961, modified 1989]