EC 18.104.22.168 - O-ureido-serine racemase
IntEnz Enzyme Nomenclature
The enzyme employs a two-base mechanism, with a thiolate-thiol pair in the active site. It participates in the biosynthetic pathway of D-cycloserine, an antibiotic substance produced by several Streptomyces species.
Links to other databases
Molecular cloning and heterologous expression of a biosynthetic gene cluster for the antitubercular agent D-cycloserine produced by Streptomyces lavendulae.Antimicrob. Agents Chemother. 54 : 1132-1139 (2010). [PMID: 20086163]
Characterization of DcsC, a PLP-independent racemase involved in the biosynthesis of D-cycloserine.Org. Biomol. Chem. 10 : 2248-2254 (2012). [PMID: 22307920]
[EC 22.214.171.124 created 2013]