EC 5.1.1.15 - 2-aminohexano-6-lactam racemase

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IntEnz Enzyme Nomenclature
EC 5.1.1.15

Names

Accepted name:
2-aminohexano-6-lactam racemase
Other name:
α-amino-ε-caprolactam racemase
Systematic name:
2-aminohexano-6-lactam racemase

Reaction

Cofactor

Comments:

contains pyridoxal 5'-phosphate. Also racemises 2-aminopentano-5-lactam (α-amino-δ-valerolactam) and 2-amino-4-thiahexano-6-lactam (where S replaces CH2 of C-4). It does not catalyse the racemisation of α-amino acids but has some transaminase activity with them.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
Gene Ontology: GO:0047463
UniProtKB/Swiss-Prot:

References

  1. Ahmed, S.A., Esaki, N., Tanaka, H., Soda, K.
    L-α-Amino-β-thio-ε-caprolactam, a new sulfur-containing substrate for α-amino-ε-caprolactam racemase.
    FEBS Lett. 174: 76-79 (1984).
  2. Ahmed, S.A., Esaki, N., Tanaka, H., Soda, K.
    Mechanism of α-amino-ε-caprolactam racemase reaction.
    Biochemistry 25: 385-388 (1986). [PMID: 3955003]

[EC 5.1.1.15 created 1999]