IntEnz

EC 4.99.1.2 - Alkylmercury lyase

IntEnz Enzyme Nomenclature
EC 4.99.1.2

Names

Reaction

• 18777 [IUBMB]
  an alkylmercury

  an alkylmercury

  Name origin: UniProt - CHECKED (C)

  CHEBI:83725

  Formula: CH2HgR
  Charge: 1

  ChEBI compound status: CHECKED (C)

  

  +

  H⁺

  H(+)

  Name origin: UniProt - CHECKED (C)

  CHEBI:15378

  Formula: H
  Charge: 1

  ChEBI compound status: CHECKED (C)

  

  =

  an alkane

  an alkane

  Name origin: UniProt - CHECKED (C)

  CHEBI:18310

  Formula: CH3R
  Charge: 0

  ChEBI compound status: CHECKED (C)

  

  +

  Hg²⁺

  Hg(2+)

  Name origin: UniProt - CHECKED (C)

  CHEBI:16793

  Formula: Hg
  Charge: 2

  ChEBI compound status: CHECKED (C)

  

Comments:

Acts on CH₃Hg⁺ and a number of other alkylmercury compounds, in the presence of cysteine or other thiols, liberating mercury as a mercaptide.

Links to other databases

References

1. Tezuka, T. and Tonomura, K.
   Purification and properties of an enzyme catalyzing the splitting of carbon-mercury linkages from mercury-resistant Pseudomonas K-62 strain. I. Splitting enzyme 1.
   J. Biochem. (Tokyo) 80: 79-87 (1976). [PMID: 9382]

[EC 4.99.1.2 created 1978]