EC - 1-aminocyclopropane-1-carboxylate synthase

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IntEnz Enzyme Nomenclature


Accepted name:
1-aminocyclopropane-1-carboxylate synthase
Other names:
1-aminocyclopropane-1-carboxylate synthetase
1-aminocyclopropane-1-carboxylic acid synthase
1-aminocyclopropanecarboxylate synthase
ACC synthase
aminocyclopropanecarboxylate synthase
aminocyclopropanecarboxylic acid synthase
S-adenosyl-L-methionine methylthioadenosine-lyase
Systematic name:
S-adenosyl-L-methionine S-methyl-5'-thioadenosine-lyase (1-aminocyclopropane-1-carboxylate-forming)




A pyridoxal 5'-phosphate protein. The enzyme catalyses an α,γ-elimination.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Protein domains and families: PROSITE:PDOC00098
Structural data: CSA , EC2PDB
Gene Ontology: GO:0016847
CAS Registry Number: 72506-68-4
UniProtKB/Swiss-Prot: (24) [show] [UniProt]


  1. Boller, T., Herner, R.C. and Kende, H.
    Assay for and enzymatic formation of an ethylene precursor, 1-aminocyclopropane-1-carboxylic acid.
    Planta 145 : 293-303 (1979).
  2. Yu, Y.-B., Adams, D.O. and Yang, S.F.
    1-Aminocyclopropanecarboxylate synthase, a key enzyme in ethylene biosynthesis.
    Arch. Biochem. Biophys. 198 : 280-296 (1979). [PMID: 507845]

[EC created 1984, modified 2021]