EC - L-tryptophan ammonia lyase

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IntEnz Enzyme Nomenclature


Accepted name:
L-tryptophan ammonia lyase
Other name:
Systematic name:
L-tryptophan ammonia-lyase (3-indoleacrylate-forming)



The enzyme, characterized from the bacterium Rubrivivax benzoatilyticus JA2, requires no cofactors. It acts on L-phenylalanine and L-glutamate with about 60% of the activity with L-tryptophan, and on L-tyrosine, glycine, and L-alanine with about 30% of the activity.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB


  1. Kumavath, R. N., Ramana, C. h. V., Sasikala, C. h., Barh, D., Kumar, A. P., Azevedo, V.
    Isolation and Characterization of L-Tryptophan Ammonia Lyase from Rubrivivax benzoatilyticus Strain JA2.
    Curr. Protein Pept. Sci. 16: 775-781 (2015). [PMID: 25961404]

[EC created 2016]