EC 4.3.1.27 - threo-3-hydroxy-D-aspartate ammonia-lyase

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IntEnz Enzyme Nomenclature
EC 4.3.1.27

Names

Accepted name:
threo-3-hydroxy-D-aspartate ammonia-lyase
Other name:
D-threo-3-hydroxyaspartate dehydratase
Systematic name:
threo-3-hydroxy-D-aspartate ammonia-lyase (oxaloacetate-forming)

Reaction

Cofactor

Comments:

A pyridoxal-phosphate protein. The enzyme, purified from the bacterium Delftia sp. HT23, also has activity against L-threo-3-hydroxyaspartate, L-erythro-3-hydroxyaspartate, and D-serine. Different from EC 4.3.1.20, erythro-3-hydroxy-L-aspartate ammonia-lyase and EC 4.3.1.16, threo-3-hydroxy-L-aspartate ammonia-lyase. Requires a divalent cation such as Mn2+, Co2+ or Ni2+.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
UniProtKB/Swiss-Prot:

References

  1. Maeda, T., Takeda, Y., Murakami, T., Yokota, A., Wada, M.
    Purification, characterization and amino acid sequence of a novel enzyme, D-threo-3-hydroxyaspartate dehydratase, from Delftia sp. HT23.
    J. Biochem. 148 : 705-712 (2010). [PMID: 20843822]

[EC 4.3.1.27 created 2010]