EC - erythro-3-hydroxy-L-aspartate ammonia-lyase

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IntEnz Enzyme Nomenclature


Accepted name:
erythro-3-hydroxy-L-aspartate ammonia-lyase
Other names:
3-hydroxyaspartate dehydratase
erythro-3-hydroxy-Ls-aspartate hydro-lyase (deaminating)
erythro-3-hydroxyaspartate dehydratase
erythro-β-hydroxyaspartate dehydratase
erythro-3-hydroxy-Ls-aspartate ammonia-lyase
Systematic name:
erythro-3-hydroxy-L-aspartate ammonia-lyase (oxaloacetate-forming)




A pyridoxal-phosphate protein. The enzyme, which was characterized from the bacterium Paracoccus denitrificans NCIMB 8944, is highly specific for the L-isomer of erythro-3-hydroxyaspartate. Different from EC, threo-3-hydroxy-L-aspartate ammonia-lyase and EC, threo-3-hydroxy-D-aspartate ammonia-lyase. Requires a divalent cation such as Mn2+, Mg2+, or Ca2+.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
Gene Ontology: GO:0047447


  1. Gibbs, R.G. and Morris, J.G.
    Purification and properties of erythro-β-hydroxyaspartate dehydratase from Micrococcus denitrificans.
    Biochem. J. 97: 547-554 (1965). [PMID: 16749162]

[EC created 1972 as EC, transfered 2001 to EC, modified 2010]