EC 4.3.1.20 - erythro-3-hydroxy-L-aspartate ammonia-lyase

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IntEnz Enzyme Nomenclature
EC 4.3.1.20

Names

Accepted name:
erythro-3-hydroxy-L-aspartate ammonia-lyase
Other names:
3-hydroxyaspartate dehydratase
erythro-3-hydroxy-Ls-aspartate hydro-lyase (deaminating)
erythro-3-hydroxyaspartate dehydratase
erythro-β-hydroxyaspartate dehydratase
erythro-3-hydroxy-Ls-aspartate ammonia-lyase
Systematic name:
erythro-3-hydroxy-L-aspartate ammonia-lyase (oxaloacetate-forming)

Reaction

Cofactor

Comments:

A pyridoxal-phosphate protein. The enzyme, which was characterized from the bacterium Paracoccus denitrificans NCIMB 8944, is highly specific for the L-isomer of erythro-3-hydroxyaspartate. Different from EC 4.3.1.16, threo-3-hydroxy-L-aspartate ammonia-lyase and EC 4.3.1.27, threo-3-hydroxy-D-aspartate ammonia-lyase. Requires a divalent cation such as Mn2+, Mg2+, or Ca2+.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
Gene Ontology: GO:0047447

References

  1. Gibbs, R.G. and Morris, J.G.
    Purification and properties of erythro-β-hydroxyaspartate dehydratase from Micrococcus denitrificans.
    Biochem. J. 97: 547-554 (1965). [PMID: 16749162]

[EC 4.3.1.20 created 1972 as EC 4.2.1.38, transfered 2001 to EC 4.3.1.20, modified 2010]