EC 4.2.99.21 - Isochorismate lyase

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IntEnz Enzyme Nomenclature
EC 4.2.99.21

Names

Accepted name:
isochorismate lyase
Other names:
salicylate biosynthesis protein pchB
pyochelin biosynthetic protein PchB
isochorismate pyruvate lyase
Systematic name:
isochorismate pyruvate-lyase (salicylate-forming)

Reaction

Comments:

This enzyme is part of the pathway of salicylate formation from chorismate, and forms an integral part of pathways that produce salicylate-derived siderophores, such as pyochelin and yersiniabactin.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
Gene Ontology: GO:0043904
UniProtKB/Swiss-Prot:

References

  1. Serino, L., Reimmann, C., Baur, H., Beyeler, M., Visca, P., Haas, D.
    Structural genes for salicylate biosynthesis from chorismate in Pseudomonas aeruginosa.
    Mol. Gen. Genet. 249: 217-228 (1995). [PMID: 7500944]
  2. Kerbarh, O., Ciulli, A., Howard, N. I., Abell, C.
    Salicylate biosynthesis: overexpression, purification, and characterization of Irp9, a bifunctional salicylate synthase from Yersinia enterocolitica.
    J. Bacteriol. 187: 5061-5066 (2005). [PMID: 16030197]

[EC 4.2.99.1 created 2010]