EC 4.2.3.99 - Labdatriene synthase

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IntEnz Enzyme Nomenclature
EC 4.2.3.99

Names

Accepted name:
labdatriene synthase
Other name:
OsKSL10 (gene name)
Systematic name:
9α-copalyl-diphosphate diphosphate-lyase [(12E)-9α-labda-8(17),12,14-triene-forming]

Reaction

Comments:

The enzyme from rice (Oryza sativa), expressed in Escherichia coli, also produces ent-sandaracopimara-8(14),15-diene from ent-copalyl diphosphate, another naturally occuring copalyl isomer in rice (cf. ent-sandaracopimaradiene synthase, EC 4.2.3.29).

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
UniProtKB/Swiss-Prot:

References

  1. Morrone, D., Hillwig, M. L., Mead, M. E., Lowry, L., Fulton, D. B., Peters, R. J.
    Evident and latent plasticity across the rice diterpene synthase family with potential implications for the evolution of diterpenoid metabolism in the cereals.
    Biochem. J. 435 : 589-595 (2011). [PMID: 21323642]

[EC 4.2.3.99 created 2012]