EC 4.2.3.89 - (+)-β-caryophyllene synthase

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IntEnz Enzyme Nomenclature
EC 4.2.3.89

Names

Accepted name:
(+)-β-caryophyllene synthase
Other name:
GcoA
Systematic name:
(2E,6E)-farnesyl-diphosphate diphosphate-lyase [cyclizing, (+)-β-caryophyllene-forming]

Reaction

Comments:

A multifunctional enzyme which also converts the (+)-β-caryophyllene to (+)-caryolan-1-ol (see EC 4.2.1.138, (+)-caryolan-1-ol synthase). cf. EC 4.2.3.57 (-)-β-caryophyllene synthase.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , DIAGRAM , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
UniProtKB/Swiss-Prot:

References

  1. Nakano, C., Horinouchi, S., Ohnishi, Y.
    Characterization of a novel sesquiterpene cyclase involved in (+)-caryolan-1-ol biosynthesis in Streptomyces griseus.
    J. Biol. Chem. 286: 27980-27987 (2011). [PMID: 21693706]

[EC 4.2.3.89 created 2011]