EC 4.2.3.73 - Valencene synthase

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IntEnz Enzyme Nomenclature
EC 4.2.3.73

Names

Accepted name:
valencene synthase
Systematic name:
(2E,6E)-farnesyl-diphosphate diphosphate-lyase (valencene-forming)

Reaction

Comments:

The recombinant enzyme from Vitis vinifera gave 49.5% (+)-valencene and 35.5% (-)-7-epi-α-selinene. Initial cyclization gives (+)-germacrene A in an enzyme bound form which is not released to the medium.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
Gene Ontology: GO:0102905
UniProtKB/Swiss-Prot:

References

  1. Lucker, J., Bowen, P., Bohlmann, J.
    Vitis vinifera terpenoid cyclases: functional identification of two sesquiterpene synthase cDNAs encoding (+)-valencene synthase and (−)-germacrene D synthase and expression of mono- and sesquiterpene synthases in grapevine flowers and berries.
    Phytochemistry 65 : 2649-2659 (2004). [PMID: 15464152]

[EC 4.2.3.73 created 2011]