EC - Patchoulol synthase

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IntEnz Enzyme Nomenclature


Accepted name:
patchoulol synthase
Systematic name:
(2E,6E)-farnesyl-diphosphate diphosphate-lyase (patchoulol-forming)


Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , DIAGRAM , DIAGRAM , DIAGRAM , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB


  1. Croteau, R., Munck, S. L., Akoh, C. C., Fisk, H. J., Satterwhite, D. M.
    Biosynthesis of the sesquiterpene patchoulol from farnesyl pyrophosphate in leaf extracts of Pogostemon cablin (patchouli): mechanistic considerations.
    Arch. Biochem. Biophys. 256 : 56-68 (1987). [PMID: 3038029]
  2. Munck, S. L., Croteau, R.
    Purification and characterization of the sesquiterpene cyclase patchoulol synthase from Pogostemon cablin.
    Arch. Biochem. Biophys. 282 : 58-64 (1990). [PMID: 2171435]
  3. Faraldos, J. A., Wu, S., Chappell, J., Coates, R. M.
    Doubly deuterium-labeled patchouli alcohol from cyclization of singly labeled [2-2H1]farnesyl diphosphate catalyzed by recombinant patchoulol synthase.
    J. Am. Chem. Soc. 132 : 2998-3008 (2010). [PMID: 20148554]

[EC created 2011]