EC 4.2.3.55 - (S)-β-bisabolene synthase

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IntEnz Enzyme Nomenclature
EC 4.2.3.55

Names

Accepted name:
(S)-β-bisabolene synthase
Systematic name:
(2E,6E)-farnesyl-diphosphate diphosphate-lyase [(S)-β-bisabolene-forming]

Reaction

Cofactor

Comments:

The synthesis of (S)-β-macrocarpene from (2E,6E)-farnesyl diphosphate proceeds in two steps. The first step is the cyclization to (S)-β-bisabolene. The second step is the isomerization to (S)-β-macrocarpene (cf. EC 5.5.1.17, (S)-β-macrocarpene synthase). The enzyme requires Mg2+ or Mn2+ for activity.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , DIAGRAM , DIAGRAM , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
UniProtKB/Swiss-Prot:

References

  1. Fujisawa, M., Harada, H., Kenmoku, H., Mizutani, S., Misawa, N.
    Cloning and characterization of a novel gene that encodes (S)-β-bisabolene synthase from ginger, Zingiber officinale.
    Planta 232 : 121-130 (2010). [PMID: 20229191]

[EC 4.2.3.55 created 2011]