EC 4.2.3.34 - Stemod-13(17)-ene synthase

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IntEnz Enzyme Nomenclature
EC 4.2.3.34

Names

Accepted name:
stemod-13(17)-ene synthase
Other names:
OsKSL11
stemodene synthase
Systematic name:
9α-copalyl-diphosphate diphosphate-lyase [stemod-13(17)-ene-forming]

Reaction

Comments:

This enzyme catalyses the committed step in the biosynthesis of the stemodane family of diterpenoid secondary metabolites, some of which possess mild antiviral activity. The enzyme also produces stemod-12-ene and stemar-13-ene as minor products.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , DIAGRAM , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB
Gene Ontology: GO:0034283
UniProtKB/Swiss-Prot:

References

  1. Morrone, D., Jin, Y., Xu, M., Choi, S.-Y., Coates, R.M. and Peters, R.J.
    An unexpected diterpene cyclase from rice: functional identification of a stemodene synthase.
    Arch. Biochem. Biophys. 448 : 133-140 (2006). [PMID: 16256063]

[EC 4.2.3.34 created 2008]