EC 4.2.3.161 - (3S)-(+)-asterisca-2(9),6-diene synthase

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IntEnz Enzyme Nomenclature
EC 4.2.3.161

Names

Accepted name:
(3S)-(+)-asterisca-2(9),6-diene synthase
Other name:
TPS2 (gene name)
Systematic name:
(2E,6E)-farnesyl-diphosphate diphosphate-lyase [cyclizing, (3S)-(+)-asterisca-2(9),6-diene-forming]

Reaction

Comments:

The sequiterpene (3S)-(+)-asterisca-2(9),6-diene has been shown to be synthezised in the slime-mold Dictyostelium discoideum. The enzyme is specific for (2E,6E)-farnesyl diphosphate.

Links to other databases

Enzymes and pathways: NC-IUBMB , BRENDA , ExplorEnz , ENZYME@ExPASy , KEGG , MetaCyc , UniPathway
Structural data: CSA , EC2PDB

References

  1. Chen, X., Kollner, T. G., Jia, Q., Norris, A., Santhanam, B., Rabe, P., Dickschat, J. S., Shaulsky, G., Gershenzon, J., Chen, F.
    Terpene synthase genes in eukaryotes beyond plants and fungi: Occurrence in social amoebae.
    Proc. Natl. Acad. Sci. U.S.A. 113 : 12132-12137 (2016). [PMID: 27790999]
  2. Rabe, P., Rinkel, J., Nubbemeyer, B., Kollner, T. G., Chen, F., Dickschat, J. S.
    Terpene Cyclases from Social Amoebae.
    Angew. Chem. Int. Ed. Engl. 55 : 15420-15423 (2016). [PMID: 27862766]

[EC 4.2.3.161 created 2017]